(E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603. IT-603 is a c-Rel inhibitor of the NF-κB family with an IC50 of 3 μM in the electrophoretic Mobility Change Test (EMSA).

 

Brand: BCM

 

GHS: GHS07

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

Signaling Pathways: NF-κB; Others

 

Isomeric SMILES: COC1=CC(=CC(=C1O)/C=C/2\C(=O)NC(=S)N2)Br  

 

InChIKey: PYLYAEDUIKQBOT-XVNBXDOJSA-N  

 

InChI: InChI=1S/C11H9BrN2O3S/c1-17-8-4-6(12)2-5(9(8)15)3-7-10(16)14-11(18)13-7/h2-4,15H,1H3,(H2,13,14,16,18)/b7-3+

 

Attribute
[Chem Name]	(5E)-5-[(5-bromo-2-hydroxy-3-methoxyphenyl)methylidene]-2-sulfanylideneimidazolidin-4-one
[Synonym]	(E/Z)-IT-603
[CAS No.]	292168-90-2
[MDL No.]	MFCD02109025
[Formula]	C11H9BrN2O3S
[Molecular]	329.17
[Form]	Solid
[Storage]	Sealed in dry, 2-8°C

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