Combretastatin A4 is a reagent that targets microtubule and binds to beta-tubulin with Kd of 0.4 μM. Phase 3.

 

Brand: BCM

 

Melting Point: 84.5-85.5°C

 

Boiling Point: 490.3±45.0 °C(Predicted)

 

pKa: 9.65±0.10(Predicted)

 

GHS: GHS05,GHS06

 

Target: Microtubule Associated

 

Signaling Pathways: Cytoskeletal Signaling

 

Solubility: Soluble in DMSO; soluble in Ethanol (warmed with 50ºC water bath). Insoluble in Water.

 

Isomeric SMILES: COC1=C(C=C(C=C1)/C=C\C2=CC(=C(C(=C2)OC)OC)OC)O  

 

InChIKey: HVXBOLULGPECHP-WAYWQWQTSA-N  

 

InChI: InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-

 

Attribute
[Chem Name]	2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol
[Synonym]	Combretastatin A4
[CAS No.]	117048-59-6
[MDL No.]	MFCD03453309
[Formula]	C18H20O5
[Molecular]	316.35
[Form]	Off-white powder
[Storage]	Keep in dark place. Inert atmosphere. Store in freezer, under -20°C

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