EN4 is a covalent ligand of cysteine 171(C171) targeting MYC and is selective for c-MYC relative to N-MYC and L-MYC. EN4 can inhibit MYC transcriptional activity, down-regulate MYC targets, and impair tumorigenesis.

 

Brand: BCM

 

Boiling Point: 564.1±50.0 °C(Predicted)

 

pKa: 12.82±0.70(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

GHS: GHS07

 

Isomeric SMILES: CCOC1=CC=C(C=C1)OC2=CC=CC=C2NC(=O)C3=CC=C(C=C3)CNC(=O)C=C  

 

InChIKey: DKOWGKKELPCHEG-UHFFFAOYSA-N  

 

InChI: InChI=1S/C25H24N2O4/c1-3-24(28)26-17-18-9-11-19(12-10-18)25(29)27-22-7-5-6-8-23(22)31-21-15-13-20(14-16-21)30-4-2/h3,5-16H,1,4,17H2,2H3,(H,26,28)(H,27,29) 

 

Attribute
[Chem Name]	N-[2-(4-ethoxyphenoxy)phenyl]-4-[(prop-2-enoylamino)methyl]benzamide
[Synonym]	EN4
[CAS No.]	1197824-15-9
[MDL No.]	MFCD13582116
[Formula]	C25H24N2O4
[Molecular]	416.47
[Storage]	4°C, protect from light

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