SI-2 hydrochloride (EPH 116 hydrochloride) is an inhibitor of steroid receptor co-activator 3 (SRC-3) with an IC50 of 3-20 nM that significantly inhibits breast tumor growth.

 

Brand: BCM

 

IC50 & Target: IC50：3-20 nM (breast cancer cell death)

 

Signaling Pathways: Angiogenesis; Tyrosine Kinase/Adaptors

 

Solubility: Soluble in DMSO; soluble in Ethanol; soluble in Water.

 

Isomeric SMILES: C/C(=N/NC1=NC2=CC=CC=C2N1C)/C3=CC=CC=N3.Cl  

 

InChIKey: CDYJHORKRVKALB-VVTVMFAVSA-N  

 

InChI: InChI=1S/C15H15N5.ClH/c1-11(12-7-5-6-10-16-12)18-19-15-17-13-8-3-4-9-14(13)20(15)2;/h3-10H,1-2H3,(H,17,19);1H/b18-11-; 

 

Attribute
[Chem Name]	1-methyl-N-[(Z)-1-pyridin-2-ylethylideneamino]benzimidazol-2-amine;hydrochloride
[Synonym]	SI-2 hydrochloride; EPH 116 Hydrochloride
[CAS No.]	1992052-49-9
[MDL No.]	MFCD30290164
[Formula]	C15H16ClN5
[Molecular]	301.78
[Form]	Solid
[Storage]	4°C. Sealed storage, away from moisture

Goods Tag