M435-1279 is a Ubiquitin-conjugating enzyme E2T (UBE2T) inhibitor that inhibits overactivation of the Wnt/ β-catenin signaling pathway by blocking UBE2T-mediated RACK1 degradation.

 

Brand: BCM

 

Target: E1/E2/E3 Enzyme

 

Signaling Pathways: Ubiquitination

 

Solubility: Soluble in DMSO. Insoluble in Ethanol; insoluble in Water.

 

Isomeric SMILES: C1CCC2=C(C1)C3=C(S2)NC(=O)C(=C3O)C(=O)NC4=CC=C(C=C4)S(=O)(=O)N  

 

InChIKey: MVQJFYRZMPKNIV-UHFFFAOYSA-N  

 

InChI: InChI=1S/C18H17N3O5S2/c19-28(25,26)10-7-5-9(6-8-10)20-16(23)14-15(22)13-11-3-1-2-4-12(11)27-18(13)21-17(14)24/h5-8H,1-4H2,(H,20,23)(H2,19,25,26)(H2,21,22,24) 

 

Attribute
[Chem Name]	4-hydroxy-2-oxo-N-(4-sulfamoylphenyl)-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-b]pyridine-3-carboxamide
[Synonym]	M435-1279
[CAS No.]	1359431-16-5
[Formula]	C18H17N3O5S2
[Molecular]	419.47
[Form]	Powder
[Storage]	Store at -20°C

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