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Tasquinimod (ABR-215050) is an orally effective antiangiogenic agent that acts by allosteric inhibition of HDAC4 signaling. Phase 3.
Brand: BCM
Boiling Point: 501.5±50.0 °C(Predicted)
pKa: 4.50±1.00(Predicted)
Solubility: Soluble in Ethanol (warmed with 50ºC water bath); soluble in DMSO. Insoluble in Water.
Isomeric SMILES: CN1C2=C(C(=CC=C2)OC)C(=C(C1=O)C(=O)N(C)C3=CC=C(C=C3)C(F)(F)F)O
InChIKey: ONDYALNGTUAJDX-UHFFFAOYSA-N
InChI: InChI=1S/C20H17F3N2O4/c1-24(12-9-7-11(8-10-12)20(21,22)23)18(27)16-17(26)15-13(25(2)19(16)28)5-4-6-14(15)29-3/h4-10,26H,1-3H3
Attribute [CAS No.] 254964-60-8 [Formula] C20H17F3N2O4 [Molecular] 406.36 [Chem Name] 4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]quinoline-3-carboxamide [Synonym] Tasquinimod; ABR-215050 [Form] Powder [Storage] Keep in dark place. Inert atmosphere. Room temperature [MDL No.] MFCD18251454
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