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Macitentan (ACT 064992) is an orally effective, non-peptide, ETA/ETB(endothelin) receptor double antagonist with an IC50 of 0.5 nM/391 nM.
Brand: BCM
Boiling Point: 692.4±65.0 °C(Predicted)
pKa: 4.99±0.50(Predicted)
Solubility: Soluble in Acetone, Ethyl acetate and Acetonitrile. Insoluble in Water and Ethanol.
Attribute [CAS No.] 441798-33-0 [MDL No.] MFCD17167076 [Formula] C19H22Br2N6O4S [Molecular] 590.295 [Chem Name] N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propylsulfamide [Synonym] Macitentan; ACT 064992 [Storage] -20℃ [EINECS] 1308068-626-2 [Form] White to off-white powder
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