Clinafloxacin (AM 1091) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro. Clinafloxacin is against DNA gyrase and topoisomerase IV of S. aureus with IC50 values of 0.92 µg/ml and 1.62 µg/ml, respectively

 

Brand: BCM

 

Melting Point: 253-258°C

 

Target: Antibacterial;  Antibiotic

 

Signaling Pathways: Microbiology/Virology

 

pKa: 6.39±0.50(Predicted)

 

Solubility: Soluble in 5%TFA; soluble in DMSO. Insoluble in Water.

 

GHS: GHS08

 

Isomeric SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C(=C32)Cl)N4CCC(C4)N)F)C(=O)O  

 

InChIKey: QGPKADBNRMWEQR-UHFFFAOYSA-N  

 

InChI: InChI=1S/C17H17ClFN3O3/c18-13-14-10(5-12(19)15(13)21-4-3-8(20)6-21)16(23)11(17(24)25)7-22(14)9-1-2-9/h5,7-9H,1-4,6,20H2,(H,24,25)

 

Attribute
[CAS No.]	105956-97-6
[Formula]	C17H17ClFN3O3
[Molecular]	365.79
[Chem Name]	7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid
[Synonym]	Clinafloxacin; CI-960; PD127391; AM-1091
[Storage]	Keep in dark place. Sealed in dry. 2-8°C
[MDL No.]	MFCD00865120
[Form]	Pale Beige Solid

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