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PD153035 HCl (SU-5271 HCl, AG1517 HCl, ZM 252868 HCl) is a potent and specific EGFR inhibitor with Ki and IC50 of 5.2 pM and 29 pM, respectively, in cell-free tests. There was little effect on PGDFR, FGFR, CSF-1, InsR and Src.
Brand: BCM
Melting Point: 265°C(lit.)
Boiling Point: 472.1°C at 760 mmHg
Solubility: Soluble in 4-Methylpyridine (warmed with 50ºC water bath); Soluble in Water. Insoluble in Water.
InChi Key: ZJOKWAWPAPMNIM-UHFFFAOYSA-N
Attribute [CAS No.] 183322-45-4 [MDL No.] MFCD01074805 [Formula] C16H14BrN3O2·HCl [Molecular] 396.67 [Chem Name] N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride [Synonym] PD153035 HCl [Storage] Sealed in dry, 2-8°C [Form] White to beige powder
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