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Canagliflozin is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively.
Brand: BCM
Target: IC50: 2/3.7/4.4 nM (m/r/hSGLT2, in CHOK cells)
Melting Point: 68 - 72°C
Boiling Point: 642.9±55.0 °C at 760 mmHg
Flashing Point: 342.6±31.5 °C
Vapour Pressure: 0.0±2.0 mmHg at 25°C
Solubility: Soluble in DMSO. Insoluble in Water and Ethnaol.
Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Attribute [CAS No.] 842133-18-0 [Formula] C24H25FO5S [Molecular] 444.53 [Chem Name] (1S)-1,5-Anhydro-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol [Synonym] Canagliflozin; JNJ 28431754; JNJ-28431754 [EINECS] 695-192-1 [MDL No.] MFCD18251436 [Form] White solid [Storage] -20 °C
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