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Empagliflozin (BI 10773) is a potent, selective SGLT-2 inhibitor with an IC50 of 3.1 nM that is 300 times more selective than that used for SGLT-1, 4, 5, and 6. Phase 3.
Brand: BCM
Melting Point: 665°C
pKa: 13.23±0.70(Predicted)
Solubility: Insoluble in H2O; ≥20.75 mg/mL in DMSO; ≥7.06 mg/mL in EtOH with ultrasonic
Isomeric SMILES: C1COC[C@H]1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl
InChIKey: OBWASQILIWPZMG-QZMOQZSNSA-N
InChI: InChI=1S/C23H27ClO7/c24-18-6-3-14(23-22(28)21(27)20(26)19(11-25)31-23)10-15(18)9-13-1-4-16(5-2-13)30-17-7-8-29-12-17/h1-6,10,17,19-23,25-28H,7-9,11-12H2/t17-,19+,20+,21-,22+,23-/m0/s1
Attribute [CAS No.] 864070-44-0 [MDL No.] MFCD22566222 [Formula] C23H27ClO7 [Molecular] 450.92 [EINECS] 620-176-8 [Form] Solid [Storage] 2-8 °C [Chem Name] (2S,3R,4R,5S,6R)-2-[4-chloro-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol [Synonym] Empagliflozin
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