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Roscovitine (CYC202, Seliciclib, R-roscovitine) is a potent and selective CDK inhibitor with IC50 of 0.65 μM, 0.7 μM, and 0.16 μM in cell-free tests on Cdc2, CDK2, and CDK5, respectively. It has little effect on CDK4/6. Phase 2.
Solubility: Soluble in DMSO and Ethanol. Insoluble in Water.
Melting Point: 106~107℃
Boiling Point: 577.5±60.0 °C(Predicted)
InChIKey: BTIHMVBBUGXLCJ-OAHLLOKOSA-N
Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Attribute [Chem Name] Roscovitine [CAS No.] 186692-46-6 [Formula] C19H26N6O [Molecular] 354.45 [MDL No.] MFCD02266401 [Synonym] CYC202, Seliciclib, R-roscovitine [Storage] -20°C [Form] White to off-white solid [Risk Codes] GHS07
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