Gdp-0941 dimethanesulfonate is an effective PI3Kα/δ inhibitor with IC50 of 3 nM. It has moderate selectivity for p110β and p110γ.

 

Brand: BCM

 

Melting Point: >280°C (dec.)

 

Target Activity: mTOR:0.58 μM (Ki), p110α-E545K:3 nM, p110α:3 nM, p110γ:75 nM, DNA-PK:1.23 μM, p110δ:3 nM, p110α-H1047R:3 nM, p110β:33 nM

 

Solubility: DMSO (Slightly, Heated), Methanol (Sparingly)

 

Attribute
[Chem Name]	GDC-0941(dimethanesulfonate)
[Synonym]	GDC-0941(2 MeSO3H salt)
[CAS No.]	957054-33-0
[Formula]	C23H27N7O3S2.2(CH4O3S)
[Molecular]	617.70
[Form]	White to pale yellow solid
[Storage]	Refrigerator

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