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PP2 is a Src family kinase inhibitor that effectively inhibits Lck/Fyn. In cell-free tests, the IC50 was 4 nM/5 nM, and the effect on EGFR was about 100 times less than that on ZAP-70, JAK2 and PKA.
Brand: BCM
Boiling Point: 493.5±40.0 °C(Predicted)
pKa: 3.96±0.30(Predicted)
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 3 mg/ml with warming). Insoluble in Water.
Attribute [CAS No.] 172889-27-9 [Formula] C15H16ClN5 [Molecular] 301.77404 [Chem Name] 3-(4-chlorophenyl)1-(1,1-diMethylethyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine [Storage] -20°C [Synonym] PP2; AG-1879 [Form] White solid [MDL No.] MFCD01568210
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