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IOX2 (JICL38) is an effective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor with an IC50 of 21 nM in cell-free assay, compared to that used in JMJD2A, JMJD2C, JMJD2E, The FIH selectivity of JMJD3 and 2OG oxygenase was more than 100 times higher.
Brand: BCM
Boiling Point: 642.8±55.0 °C(Predicted)
pKa: 3.61±0.10(Predicted)
Solubility: Soluble in DMSO. Insoluble in Water.
InChi Key: CAOSCCRYLYQBES-UHFFFAOYSA-N
Attribute [Chem Name] IOX2 [CAS No.] 931398-72-0 [EINECS] 804-733-4 [Formula] C19H16N2O5 [Molecular] 352.34 [Storage] 2-8°C [Synonym] N-[[1,2-Dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]glycine [MDL No.] MFCD22580424 [Form] White to beige powder
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