GNF-7 is a potent type II kinase Bcr-Abl inhibitor with an IC50 of <5 nM, 61 nM, 122 nM, 136 nM, and 133 nM for M351T, T315I, E255 V, G250E, and c-Abl, respectively.

 

Brand: BCM

 

pKa: 12.82±0.70(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Water and Ethanol.

 

Attribute
[CAS No.]	839706-07-9
[Formula]	C28H24F3N7O2
[Molecular]	547.53
[Chem Name]	BenzaMide, N-[3-[1,4-dihydro-1-Methyl-7-[(6-Methyl-3-pyridinyl)aMino]-2-oxopyriMido[4,5-d]pyriMidin-3(2H)-yl]-4-Methylphenyl]-3-(trifluoroMethyl)-
[Synonym]	GNF-7; GNF 7; GNF7
[MDL No.]	MFCD18251569
[Form]	Solid

Goods Tag