Nutlin-3 is a potent, selective Mdm2(ring-finger-dependent ubiquitin protein ligase of itself and p53) antagonist with an IC50 of 90 nM in cell-free trials. It can stabilize p73 in p53 deficient cells.

 

Brand: BCM

 

pKa: 14.35±0.20(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Water.

 

Attribute
[CAS No.]	890090-75-2
[Formula]	C30H30Cl2N4O4
[Molecular]	581.494
[Chem Name]	4-(4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one
[Storage]	Sealed in dry. Room Temperature
[Synonym]	Nutlin-3
[MDL No.]	MFCD07784509
[Form]	Solid

Goods Tag