HS-1371 is a potent inhibitor of RIP3 kinase with an IC50 of 20.8 nM. It binds to the ATP-binding region of RIP3, thereby preventing ATP binding and inhibiting RIP3 enzymatic activity in vitro.

 

Brand: BCM

 

Target: RIP3:20.8 nM

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

GHS: GHS07

 

Isomeric SMILES: CC1=CC=C(C=C1)OC2=C3C=CC(=CC3=NC=C2)C4=CN(N=C4)C5CCNCC5  

 

InChIKey: VPVLPCIBKVWFDT-UHFFFAOYSA-N  

 

InChI: InChI=1S/C24H24N4O/c1-17-2-5-21(6-3-17)29-24-10-13-26-23-14-18(4-7-22(23)24)19-15-27-28(16-19)20-8-11-25-12-9-20/h2-7,10,13-16,20,25H,8-9,11-12H2,1H3

 

Attribute
[CAS No.]	2158197-70-5
[Formula]	C24H24N4O
[Molecular]	384.47
[Chem Name]	4-(4-methylphenoxy)-7-(1-piperidin-4-ylpyrazol-4-yl)quinoline
[Storage]	Keep in dark place. Inert atmosphere. Room temperature
[Synonym]	HS1371; HS-1371
[MDL No.]	MFCD31813738
[Form]	Solid powder

Goods Tag