Alisol B acetate, a triterpene from Alismatis rhizoma, induces Bax up-regulation and nuclear translocation, the activation of initiator caspase-8 and caspase-9, and executor caspase-3, suggesting the involvement of both extrinsic and intrinsic apoptosis pathways.

 

Brand: BCM

 

Melting Point: 162～163℃

 

Boiling Point: 590.7±50.0 °C(Predicted)

 

pKa: 14.74±0.70(Predicted)

 

GHS: GHS07

 

Solubility: Soluble in DMSO. Slightly soluble in Chloroform.

 

Isomeric SMILES: C[C@H](C[C@@H]([C@@H]1C(O1)(C)C)OC(=O)C)C2=C3C[C@@H]([C@H]4[C@]5(CCC(=O)C([C@@H]5CC[C@@]4([C@]3(CC2)C)C)(C)C)C)O  

 

InChIKey: NLOAQXKIIGTTRE-JSWHPQHOSA-N  

 

InChI: InChI=1S/C32H50O5/c1-18(16-23(36-19(2)33)27-29(5,6)37-27)20-10-14-31(8)21(20)17-22(34)26-30(7)13-12-25(35)28(3,4)24(30)11-15-32(26,31)9/h18,22-24,26-27,34H,10-17H2,1-9H3/t18-,22+,23+,24+,26+,27-,30+,31+,32+/m1/s1

 

Attribute
[CAS No.]	26575-95-1
[Formula]	C32H50O5
[Molecular]	514.7364
[MDL No.]	MFCD00210473
[Chem Name]	[(1S,3R)-1-[(2R)-3,3-dimethyloxiran-2-yl]-3-[(5R,8S,9S,10S,11S,14R)-11-hydroxy-4,4,8,10,14-pentamethyl-3-oxo-1,2,5,6,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-17-yl]butyl] acetate
[Storage]	Keep in dark place. Sealed in dry, 2-8°C
[Synonym]	Alisol B Acetate
[Form]	White solid

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