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SN-38, an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis, and causes frequent DNA single strand breaks.
Brand: BCM
Melting Point: 217 °C
Boiling Point: 810.3±65.0 °C(Predicted)
pKa: 9.13±0.40(Predicted)
Solubility: Soluble in DMSO. Insoluble in Water.
InChIKey: FJHBVJOVLFPMQE-QFIPXVFZSA-N
Attribute [CAS No.] 86639-52-3 [Formula] C22H20N2O5 [Molecular] 392.4 [Chem Name] (S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione [Synonym] SN-38 [Storage] 2-8 °C [EINECS] 643-093-9 [MDL No.] MFCD06762720 [Form] Off-white powder
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