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Functionalized PEG can be used to modify proteins, peptides, and materials. Functionalized PEG can also increase solubility and stability, and reduce the immunogenicity of peptides and proteins. It can also inhibit nonspecific binding of charged molecules to modify surfaces.
Amino (NH2) can modify active groups that can react with primary amines, form stable amide bonds with carboxyl groups (-COOH), and form amide bonds with active esters (NHS) at PH7-8.5. Maleimide and sulfhydryl groups can easily form stable sulfur ether bonds at PH6.5-7.5. Peg increases drug solubility and stability, reduces immunogenicity of peptides and proteins, inhibits nonspecific binding of charged molecules on modified surfaces, and can modify proteins, peptides and other small molecular materials. Widely used in medical research, drug release, nano new materials research, cell culture, in the ligand study of active compounds, polypeptide synthesis carrier, polymer grafting compounds, new materials of polyethylene glycol coating and modification functionalization of applications has become a research trend.
Brand: BCM
Solubility: Soluble in water, chloroform, DMSO, dichloromethane and other conventional organic solvents.
Attribute [Chem Name] Maleimide PEG Amine [Synonym] NH2-PEG-Mal [Molecular] (PEG) : 2000, 3400, 5000, other molecular weights can be customized. [Form] White solid or viscous liquid, depending on the size of molecular weight. [Storage] Cold chain storage at 2-8 degrees Celsius
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