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Mifamurtide is a liposomal formulation containing a muramyl dipeptide (MDP) analogue with potential immunomodulatory and antineoplastic activities.. Muramyl tripeptide phosphatidylethanolamine (MTP-PE), a derivative of the mycobacterial cell wall component MDP, activates both monocytes and macrophages. Activated macrophages secrete cytokines and induce the recruitment and activation of other immune cells, which may result in indirect tumoricidal effects. Liposomal encapsulation of MTP-PE prolongs its half-life and enhances tissue targeting. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
Brand: BCM
Solubility: Soluble in DMSO. Insoluble in Water.
InChi Key: JMUHBNWAORSSBD-ZXSMYVEWSA-N
Attribute [CAS No.] 83461-56-7 [Formula] C59H109N6O19P [Molecular] 1237.5 [Chem Name] N-Acetylmuramyl-alanyl-isoglutaminyl-alanyl-sn-glycero-3-phosphoethano lamine [Synonym] Mifamurtide [Storage] -20°C [MDL No.] MFCD09954133 [Form] White to beige powder
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