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Pepstatin A is a pentapeptide isolated from Streptomyces testaceus. It is a potent inhibitor of aspartyl proteases. It has a role as a bacterial metabolite and an EC 3.4.23.* (aspartic endopeptidase) inhibitor. It is a pentapeptide and a secondary carboxamide. It is a conjugate acid of a pepstatin A(1-).
Brand: BCM
Usage: Dissolved in a mixture of 10% acetic acid and methanol (acetic acid to methanol ratio is 1:9)
European Community (EC) Number: 247-600-0
Melting point: 220 ~ 240℃
Boiling point: 997.6℃ at 760 mmHg
Specific Rotation: -85 ~ -95° (0.5%, MeOH)
Sensitivity: Sensitivity to heat
Solubility: Soluble in DMSO; soluble in Ethanol (warmed with 50ºC water bath). Insoluble in Water.
InChIKey: FAXGPCHRFPCXOO-LXTPJMTPSA-N
Attribute [CAS No.] 26305-03-3 [Formula] C34H63N5O9 [Molecular] 685.89 [MDL No.] MFCD00060740 [Chem Name] (3S,4S)-3-hydroxy-4-[[(2S)-2-[[(3S,4S)-3-hydroxy-6-methyl-4-[[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]butanoyl]amino]heptanoyl]amino]propanoyl]amino]-6-methylheptanoic acid [Synonym] Pepstatin A [Storage] Sealed in dry. 2-8°C [EINECS] 247-600-0 [Form] White solid powder
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