Name：Capmatinib

Catalog No.：
BCM005892

Chem Name：
Capmatinib

Synonym：
Capmatinib; INC280, INCB 28060; NVP-INC280; INC 280; INCB028060; NVP INC280; INCB28060; INCB-28060; NVPINC280; INC280; INC-280; INCB-028060; INCB 028060;

CAS No.：
1029712-80-8

Formula：
C23H17FN6O

Molecular：
412.42

Storage：
Sealed storage

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SKU	Specification	Brand	Prices	Stock	Cart
BCM005892-250MG	250mg， Purity:98%	BCM	$224	2	Add Cart
BCM005892-500MG	500mg， Purity:98%	BCM	$352	2	Add Cart
BCM005892-1G	1g， Purity:98%	BCM	$610	2	Add Cart
BCM005892-5G	5g， Purity:98%	BCM	$1581	2	Add Cart

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Description: Capmatinib (formerly also known as INCB-28060; INC280; Tabrecta) is a novel, potent, orally bioavailable, ATP-competitive inhibitor of c-MET with potential antitumor activity. It inhibits c-MET with an IC50 of 0.13 nM in a cell-free assay, and is inactive against RONβ, as well as EGFR and HER-3. Capmatinib has gained approval for the treatment of adults with metastatic non-small cell lung cancer. c-Met inhibitor INC280 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing constitutively activated c-Met protein.

Attribute

[Chem Name] Capmatinib

[Synonym] Capmatinib; INC280, INCB 28060; NVP-INC280; INC 280; INCB028060; NVP INC280; INCB28060; INCB-28060; NVPINC280; INC280; INC-280; INCB-028060; INCB 028060;

[CAS No.] 1029712-80-8

[Formula] C23H17FN6O

[Molecular] 412.42

[Storage] Sealed storage

Attribute
[Chem Name]	Capmatinib
[Synonym]	Capmatinib; INC280, INCB 28060; NVP-INC280; INC 280; INCB028060; NVP INC280; INCB28060; INCB-28060; NVPINC280; INC280; INC-280; INCB-028060; INCB 028060;
[CAS No.]	1029712-80-8
[Formula]	C23H17FN6O
[Molecular]	412.42
[Storage]	Sealed storage