Description: Chrysophanic acid (also called Chrysophanol), a naturally occuring anthraquinone isolated from Dianella longifolia, is a selective and potent inhibitor of EGFR/mTOR (epidermal growth factor (EGF) receptor/mammalian target of rapamycin) with potential anti-obesity and antitumor activity. Chrysophanol (CA) improves high-fat diet (HFD)-induced obesity in C57BL/6 Mice. It also showed potent antiproliferative and ancticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells. It preferentially blocked proliferation of SNU-C5 cells but not in other cell lines with low levels of EGFR expression.

 

References: Phytother Res. 2011 Jun;25(6):833-7; Antiviral Res. 2001 Mar;49(3):169-78.  

Attribute
[Chem Name]	Chrysophanic Acid
[Synonym]	1,8-dihydroxy-3-methylanthracene-9,10-dione
[CAS No.]	481-74-3
[Formula]	C15H10O4
[Molecular]	254.24
[Storage]	-20℃ for 3 years in powder form
[EINECS]	207-572-2
[MDL No.]	MFCD00001208
[Form]	Yellow-orange crystalline
[Risk Codes]	GHS07

Goods Tag