Biological Activity:

 

Elobixibat was an effective inhibitor of ilealbileacidtransporter(IBAT) with IC50 values of 0Chemicalbook.53±0.17nM(human IBAT) and 0.13±0.03nM(mouse IBAT), respectively. 5.8±1.6nM(canine IBAT).

 

Attribute
[Chem Name]	Elobixibat
[CAS No.]	439087-18-0
[Synonym]	Glycine,(2R)-N-(2-((3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-1,1-dioxido-5-phenyl-1,5-benzothiazepin-8-yl)oxy)acetyl)-2-phenylglycyl; UNII-865UEK4EJC; A3309; AZD-7806; Elobixibat [INN]; 2-[[(2R)-2-[[2-[(3,3-dibutyl-7-methylsulfanyl-1,1-dioxo-5-phenyl-2,4-dihydro-1λ6,5-benzothiazepin-8-yl)oxy]acetyl]amino]-2-phenylacetyl]amino]acetic acid; N-{(2R)-2-[({[3,3-Dibutyl-7-(methylsulfanyl)-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-8-yl]oxy}acetyl)amino]-2-phenylacetyl}glycine;
[Formula]	C₃₆H₄₅N₃O₇S₂
[Molecular]	695.89
[MDL No.]	MFCD28386301

Goods Tag