Norcantharidin (Endothall anhydride) is a synthetic anticancer compound which is a dual inhibitor for c-Met and EGFR in human colon cancers.

 

Brand: BCM

 

Target: EGFR; c-Met/HGFR

 

Signaling Pathways: Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors

 

Boiling Point: 362.5±35.0 °C at 760 mmHg

 

Flashing Point: 167.0±26.0 °C

 

Melting Point: 110°C

 

Stability: Hygroscopic, Moisture Sensitive

 

Vapour Pressure: 0.0±0.8 mmHg at 25°C

 

Solubility: Soluble in DMSO.

GHS: GHS07

 

Isomeric SMILES: C1C[C@H]2[C@H]3[C@@H]([C@@H]1O2)C(=O)OC3=O  

 

InChIKey: JAABVEXCGCXWRR-FBXFSONDSA-N  

 

InChI: InChI=1S/C8H8O4/c9-7-5-3-1-2-4(11-3)6(5)8(10)12-7/h3-6H,1-2H2/t3-,4+,5-,6+

 

Attribute
[CAS No.]	5442-12-6
[EINECS]	637-280-4
[MDL No.]	MFCD00213361
[Formula]	C8H8O4
[Molecular]	168.15
[Form]	White to off-white solid
[Risk Codes]	H315-H319-H335
[Synonym]	Demehylcantharidin; Norcantharidin; Endothall anhydride
[Chem Name]	Hexahydro-4,7-epoxyisobenzofuran-1,3-dione
[Storage]	Hygroscopic. Room Temperature. Under inert atmosphere

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