p97-IN-1 is a potent p97 inhibitor with an IC50 <30 nM (WO2015109285A1, compound FF07)[1].

 

Brand: BCM

 

Signaling Pathways: Ubiquitination

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

Isomeric SMILES: CC1=CC2=C(C=CC=C2N1C3=NC4=C(CCCN4)C(=N3)NCC5=CC=CC=C5)C(=O)N  

 

InChIKey: XDHFSLWWYBVSLN-UHFFFAOYSA-N  

 

InChI: InChI=1S/C24H24N6O/c1-15-13-19-17(21(25)31)9-5-11-20(19)30(15)24-28-22-18(10-6-12-26-22)23(29-24)27-14-16-7-3-2-4-8-16/h2-5,7-9,11,13H,6,10,12,14H2,1H3,(H2,25,31)(H2,26,27,28,29)

 

References: [1]. David Wustrow, et al. FUSED PYRIMIDINES AS INHIBITORS OF p97 COMPLEX. WO2015109285A1.

 

Attribute
[CAS No.]	1863952-15-1
[Formula]	C24H24N6O
[Molecular]	412.49
[Chem Name]	1-[4-(benzylamino)-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-2-yl]-2-methylindole-4-carboxamide
[Synonym]	p97-IN-1; CB-5339
[Form]	Solid
[Storage]	Powder: -20°C for 3 years. In solvent: -80°C for 2 years

Goods Tag