Eltrombopag (SB-497115), a small molecule of biarylhydrazone, is a non-peptide agonist for thrombopoietin receptor (TpoR). For the treatment of chronic hepatitis C associated thrombocytopenia and chronic immune (spontaneous) thrombocytopenia (ITP).

 

Brand: BCM

 

Target: thrombopoietin receptor (TpoR)

 

Solubility: Soluble in DMSO and Ethanol.

 

Melting Point: 242-244°C

 

Storage: Stored at normal temperature with tight seal.

 

Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

 

Isomeric SMILES: CC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)N=NC3=CC=CC(=C3O)C4=CC(=CC=C4)C(=O)O)C  

 

InChIKey: SVOQIEJWJCQGDQ-UHFFFAOYSA-N  

 

InChI: InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,28,30H,1-3H3,(H,32,33) 

 

Attribute
[Storage]	Keep in dark place. Inert atmosphere. Room temperature
[Chem Name]	3-[3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid
[Synonym]	Eltrombopag
[CAS No.]	496775-61-2
[EINECS]	610-469-9
[MDL No.]	MFCD20926253
[Formula]	C25H22N4O4
[Molecular]	442.47
[Form]	Orange red solid

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