Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease. It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport via peritoneal lymphatic pathways. 

Icodextrin is a starch-derived glucose polymer that produces ultrafiltration by exerting colloid oncotic pressure when administered intraperitoneally. [1]

 

Solubility: Soluble in water (80 mg/mL).

 

PSA: 325.83000

 

Boiling Point: 969.6°C at 760 mmHg

 

Reference: [1] National Kidney Foundation Primer on Kidney Diseases (Sixth Edition), 2014

 

Attribute
[Chem Name]	4-bromo-2,5-dimethoxybenzene-1-sulfonyl chloride
[Synonym]	Icodextrin
[CAS No.]	337376-15-5
[Formula]	C46H62N4O11
[EINECS]	211-148-2
[Molecular]	847.0047
[Form]	Solid

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