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MRTX-1257
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Name:MRTX-1257

  • Catalog No.:
  • BCM006407
  • Chem Name:
  • 2-((S)-1-acryloyl-4-(7-(8-methylnaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)piperazin-2-yl)acetonitrile
  • Synonym:
  • MRTX1257; MRTX-1257
  • CAS No.:
  • 2206736-04-9
  • MDL No.:
  • MFCD31813777
  • Formula:
  • C33H39N7O2
  • Molecular:
  • 565.71
  • Form:
  • Solid powder
  • Risk Codes:
  • GHS07
  • Storage:
  • Store lyophilized at -20ºC, keep desiccated.
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SKU Specification Brand Prices Stock Quantity Cart
BCM006407-10MG 10mg, Purity:98% BCM $225 2 Add Cart
BCM006407-25MG 25mg, Purity:98% BCM $383 2 Add Cart
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MRTX1257 is a potent, selective, covalent and irreversible inhibitor of KRAS G12C, MRTX1257 inhibited KRAS dependent ERKphosphorylation in the H358cell assay with an IC50= 900 pM.

 

Boiling Point: 845.5±75.0 °C(Predicted)

 

Solubility: Soluble in DMSO and Ethanol. Insoluble in Water.

 

 

Attribute
[Chem Name] 2-((S)-1-acryloyl-4-(7-(8-methylnaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)piperazin-2-yl)acetonitrile
[Synonym] MRTX1257; MRTX-1257
[CAS No.] 2206736-04-9
[MDL No.] MFCD31813777
[Formula] C33H39N7O2
[Molecular] 565.71
[Form] Solid powder
[Risk Codes] GHS07
[Storage] Store lyophilized at -20ºC, keep desiccated.

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