PluriSln-1, also known as PluriSln #1 and NSC 14613, is pluripotent cell-specific inhibitor (PluriSIn). PluriSIn #1 induces ER stress, protein synthesis attenuation, and apoptosis in hPSCs. PluriSIn #1 was also cytotoxic to mouse blastocysts, indicating that the dependence on oleate is inherent to the pluripotent state. The use of human pluripotent stem cells (hPSCs) in cell therapy is hindered by the tumorigenic risk from residual undifferentiated cells.

 

Brand: BCM

 

Solubility: DMSO: soluble15mg/mL, clear

 

Melting Point: 177-178℃

 

Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

 

Attribute
[Synonym]	4-Pyridinecarboxylicacid,2-phenylhydrazide;plurisln1;1,4-Pyridinecarboxylicacid;NSC14613;NSC-14613;NSC1Chemicalbook4613;PluriSIn#1-NSC14613|Pluripotentcell-specificinhibitor#1;NSC14613,PluriSln1,>98%;NSC14613;PluriSIn#1
[CAS No.]	91396-88-2
[EINECS]	804-702-5
[MDL No.]	MFCD02344904
[Formula]	C12H11N3O
[Molecular]	213.24
[Form]	White to beige powder
[Risk Codes]	GHS07
[Storage]	Sealed in dry. Store in freezer, under -20°C
[Chem Name]	N'-phenylisonicotinohydrazide

Goods Tag