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G5-7 is an oral active allosteric JAK2 inhibitor that selectively inhibits Jak2-mediated EGFR (Tyr1068) and STAT3 phosphorylation and activation by binding to JAK2.
Solubility: Soluble in DMSO and Ethanol. Insoluble in Water.
PSA: 46.61000
LogP: 5.18950
HS CODE: 2933399090
InChIKey: MCSPIRBNMDODQP-BKHHGCLFSA-N
Attribute [Chem Name] tert-Butyl 3,5-bis(2-fluorobenzylidene)-4-oxopiperidine-1-carboxylate [Synonym] JAK2 inhibitor G5-7 [CAS No.] 939681-36-4 [MDL No.] MFCD21603655 [Formula] C22H19F2NO3 [Molecular] 383.39 [Risk Codes] GHS07 [Storage] Dry, sealed place.
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