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LQZ-7I is a novel selective inhibitor of survivin dimerization, with IC50 of 4.8 µM in PC-3 and 3.1 µM in C4-2. LQZ-7I effectively inhibited the growth of xenograft tumors and induced the loss of survival proteins in the tumors.
Brand: BCM
Melting Point: 203 °C(Solv: ethanol (64-17-5))
Boiling Point: 470.3±45.0 °C(Predicted)
pKa: 2.56±0.59(Predicted)
Solubility: Soluble in DMSO and Ethanol. Insoluble in Water.
InChi Key: DKPCKOKYSVPFEB-UHFFFAOYSA-N
Attribute [Synonym] LQZ-7I; LQZ 7I; LQZ7I; [CAS No.] 195822-23-2 [MDL No.] MFCD00607076 [Formula] C20H14F2N4 [Molecular] 348.35 [Form] Solid powder [Storage] Keep in dark place. Inert atmosphere. Room temperature [Chem Name] 2,3-Quinoxalinediamine, N,N'-bis(4-fluorophenyl)-
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