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ML192, also known as MLS000526305 and CID1434953, is a selective ligands for GPR55. The orphan G protein coupled receptor, ML192 (CID1434953) with 1080 nM potency for GPR55 and >45-fold antagonist and agonist selectivity against GPR35, CB1 and CB2. GPR55 has gained notoriety because of its putative identification as a cannabinoid receptor subtype. The significance of this assignment should not be underestimated given the importance of cannabinoids to drug abuse and the potential utility of cannabinoid ligands in treating behavioral disorders leading to conditions such as obesity.
Brand: BCM
Solubility: Soluble in DMSO, not in water
InChi Key: GDPDARVUXXOYAJ-UHFFFAOYSA-N
Attribute [Chem Name] furan-2-yl(4-(2-methyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)methanone [Synonym] ML192; ML 192; ML-192; CID1434953; CID-1434953; CID 1434953; MLS000526305 [CAS No.] 460331-61-7 [MDL No.] MFCD03127624 [Formula] C20H22N4O2S [Molecular] 382.47928 [Form] Solid powder
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