AZD8797 is a non-competitive, oral allosteric modulator of human CX3CR1, antagonizing CX3CR1 and CXCR2 at 3.9 and 2800 nM Ki, respectively.

 

Brand: BCM

 

Boiling Point: 651.1±65.0 °C(Predicted)

 

Flashing Point: 347.6±34.3 °C

 

pKa: 14.47±0.10(Predicted)

 

Target: [125I]-CX3CL1-CX3CR1:3.9 nM (Ki, in HEK293S cells);   125I-IL-8-CXCR2:2800 nM (Ki, in HEK293S cells)

 

Solubility: Soluble in DMSO

 

InChi Key: ZMQSLMZOWVGBSM-GXTWGEPZSA-N

 

Attribute
[Chem Name]	(2R)-2-[[2-Amino-5-[(1S)-1-phenylethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
[Synonym]	CX3CR1 antagonist 18a; CX3CR1-antagonist-18a; CX3CR1antagonist18a; CX3CR1-IN-18a; CX3CR1IN18a; CX3CR1 IN 18a
[CAS No.]	911715-90-7
[MDL No.]	MFCD28139065
[Formula]	C19H25N5OS2
[Molecular]	403.56
[Form]	Solid powder
[Storage]	2-8℃

Goods Tag