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(S)-(+)-3-Hydroxytetrahydrofuran is indicated for first-line treatment of advanced non-small cell lung cancer (NSCLC) and as an intermediate of the active drug afatinib in HER2-positive advanced breast cancer patients; Afatinib intermediate
Brand: BCM
Boiling Point: 80℃15 mmHg(lit.)
Specific Rotation: 18.5°(c=2 MeOH)
Flash Point: 81.1℃
pKa: 14.49±0.20(Predicted)
Optical Activity: [α]20/D +17.5°, c = 2.4 in methanol
Solubility: Chloroform, Methanol (Slightly)
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
Attribute [Chem Name] (S)-(+)-3-Hydroxytetrahydrofuran [Synonym] (3S)-Tetrahydro-3-furanol; Tetrahydrofuran-3-ol [CAS No.] 86087-23-2 [EINECS] 425-090-2 [MDL No.] MFCD00064327 [Formula] C4H8O2 [Molecular] 88.11 [Form] Colorless liquid [Storage] Keep in dark place. Sealed in dry. Room Temperature
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