Name：Cabozantinib S-Malate

Catalog No.：
BCM006532

Chem Name：
N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-2-hydroxysuccinate

Synonym：
XL-184; XL184; XL 184; BMS907351; BMS 907351; BMS-907351; Cabozantinib malate; Cabozantinib S-malate

CAS No.：
1140909-48-3

EINECS：
691-711-0

MDL No.：
MFCD20923480

Formula：
C32H30FN3O10

Molecular：
635.6

Form：
White to off-white solid

Storage：
Sealed in dry. Room Temperature

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SKU	Specification	Brand	Prices	Stock	Cart
BCM006532-5G	5g, Purity:98%	BCM	$30	2	Add Cart
BCM006532-10G	10g, Purity:98%	BCM	$53	2	Add Cart
BCM006532-25G	25g, Purity:98%	BCM	$125	5	Add Cart
BCM006532-50G	50g, Purity:98%	BCM	$240	3	Add Cart
BCM006532-100G	100g, Purity:98%	BCM	$466	4	Add Cart
BCM006532-250G	250g, Purity:98%	BCM	$1128	2	Add Cart

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Product Description

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Cabozantinib malate (XL184), the malate of Cabozantinib, is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, RET (c-RET), Kit (c-Kit), Flt-1/3/4, The IC50 values of Tie2 and AXL were 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Cabozantinib malate (XL184) can induce apoptosis.

Brand: BCM

Melting Point: 166-169°C

Target: VEGFR2:0.035 nM (IC50)

Solubility: Soluble in DMSO. Insoluble in Water and Ethanol.

InChi Key: HFCFMRYTXDINDK-WNQIDUERSA-N

Attribute

[Chem Name] N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-2-hydroxysuccinate

[Synonym] XL-184; XL184; XL 184; BMS907351; BMS 907351; BMS-907351; Cabozantinib malate; Cabozantinib S-malate

[CAS No.] 1140909-48-3

[EINECS] 691-711-0

[MDL No.] MFCD20923480

[Formula] C32H30FN3O10

[Molecular] 635.6

[Form] White to off-white solid

[Storage] Sealed in dry. Room Temperature

Attribute
[Chem Name]	N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-2-hydroxysuccinate
[Synonym]	XL-184; XL184; XL 184; BMS907351; BMS 907351; BMS-907351; Cabozantinib malate; Cabozantinib S-malate
[CAS No.]	1140909-48-3
[EINECS]	691-711-0
[MDL No.]	MFCD20923480
[Formula]	C32H30FN3O10
[Molecular]	635.6
[Form]	White to off-white solid
[Storage]	Sealed in dry. Room Temperature