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Sacubitril/valsartan (LCZ696, Sacubitril, Valsartan), by valsartan and sacubitril with 1: angiotensin receptor-neprilysin inhibitor (ARNi) is an oral bioactive, dual-acting angiotensin receptor-Neprilysin inhibitor (ARni) for the treatment of hypertension and heart failure. Phase 3.
Brand: BCM
Target: RAAS
Solubility: Soluble in DMSO (warmed with 50ºC water bath); soluble in Water (warmed with 50ºC water bath); soluble in Ethanol (warmed with 50ºC water bath).
InChi Key: UOLUPHRXIRFONO-JOYYXRJNSA-K
Attribute [Chem Name] sodium (S)-5-(4'-((N-(1-carboxylato-2-methylpropyl)pentanamido)methyl)-[1,1'-biphenyl]-2-yl)tetrazol-1-ide 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate hydrate [Synonym] LCZ696; LCZ-696; LCZ 696. valsartan / sacubitril (1:1). [CAS No.] 936623-90-4 [MDL No.] MFCD29477717 [Formula] C96H120N12Na6O21 [Molecular] 1915.99 [Form] Solid powder
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