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Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM.
Brand: BCM
Solubility: Soluble in DMSO.
InChIKey: XYWIPYBIIRTJMM-IBGZPJMESA-N
Attribute [Chem Name] 4-[[(2S)-2-[4-[5-chloro-2-[4-(trifluoromethyl)triazol-1-yl]phenyl]-5-methoxy-2-oxopyridin-1-yl]butanoyl]amino]-2-fluorobenzamide [Synonym] Asundexian; BAY-2433334 [CAS No.] 2064121-65-7 [MDL No.] MFCD34578251 [Formula] C26H21ClF4N6O4 [Molecular] 592.93 [Form] White to off-white Solid [Storage] Sealed in dry. Stored at -20°C.
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