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OSI-930 is a selective thiophene-derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI-930 inhibits stem cell factor receptor (c-Kit) and the vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of both tumor cell proliferation and tumor angiogenesis. Both c-Kit and VEGFR2 are overexpressed in a variety of cancers. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
Brand: BCM
Boiling Point: 517.4±50.0 °C(Predicted)
pKa: 11.36±0.70(Predicted)
Solubility: Soluble in DMSO. Insoluble in Water.
InChi Key: FGTCROZDHDSNIO-UHFFFAOYSA-N
Attribute [Chem Name] 3-((Quinolin-4-ylmethyl)amino)-N-(4-(trifluoromethoxy)phenyl)thiophene-2-carboxamide [Synonym] OSI-930 [CAS No.] 728033-96-3 [MDL No.] MFCD11100358 [Formula] C22H16F3N3O2S [Molecular] 443.44 [Form] Solid [Storage] Keep in dark place. Inert atmosphere,2-8°C
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