KR-32568 is an inhibitor of the sodium-hydrogen exchanger isoform-1 (NHE-1; IC50 = 230 nM). It restores cardiac contractile function ex vivo in an isolated ischemic rat heart model when used at a concentration of 10 μM. KR-32568 (0.3 mg/kg) reduces myocardial infarct size in a rat model of ischemia and reperfusion injury.

 

Brand: BCM

 

Melting Point: 176 °C

 

pKa: 7.31±0.46(Predicted)

 

Solubility: Soluble in DMSO.

 

Isomeric SMILES: CC1=C(C=C(C=C1)F)C2=CC=C(O2)C(=O)N=C(N)N  

 

InChIKey: DTLDHYBZLVASJQ-UHFFFAOYSA-N  

 

InChI: InChI=1S/C13H12FN3O2/c1-7-2-3-8(14)6-9(7)10-4-5-11(19-10)12(18)17-13(15)16/h2-6H,1H3,(H4,15,16,17,18)  

 

Attribute
[Chem Name]	N-(aminoiminomethyl)-5-(5-fluoro-2-methylphenyl)-2-furancarboxamide
[Synonym]	KR-32568; KR 32568; KR32568
[CAS No.]	852146-73-7
[MDL No.]	MFCD08705324
[Formula]	C13H12FN3O2
[Molecular]	261.25
[Form]	White solid
[Storage]	Sealed in dry. 2-8°C

Goods Tag