GNF-PF-3777 (8-Nitrotryptanthrin) is an effective inhibitor of human indoleamine 2, 3-dioxygenase 2, hIDO2 with a Ki value of 0.97 μM. IDO2 activity can be significantly reduced.

 

Brand: BCM

 

Melting Point: >250 °C

 

Boiling Point: 551.2±52.0 °C(Predicted)

 

pKa: -7.55±0.20(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Ethanol; insoluble in Water.

 

Isomeric SMILES: C1=CC=C2C(=C1)C(=O)N3C4=C(C=C(C=C4)[N+](=O)[O-])C(=O)C3=N2  

 

InChIKey: UFMQJYHLIUACCG-UHFFFAOYSA-N  

 

InChI: InChI=1S/C15H7N3O4/c19-13-10-7-8(18(21)22)5-6-12(10)17-14(13)16-11-4-2-1-3-9(11)15(17)20/h1-7H

 

Attribute
[Chem Name]	8-nitroindolo[2,1-b]quinazoline-6,12-dione
[Synonym]	GNF-PF-3777; 8-Nitrotryptanthrin
[CAS No.]	77603-42-0
[MDL No.]	MFCD00618023
[Formula]	C15H7N3O4
[Molecular]	293.23
[Form]	A crystalline solid
[Storage]	Inert atmosphere. Room Temperature

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