Perifosine (KRX-0401, NSC639966, D21266) is a novel Akt inhibitor with IC50 of 4.7 μM in MM.1S cells that targets the pleckstrin homologous domain of Akt. Phase 3.

 

Brand: BCM

 

Melting Point: 271-272° (dec)

 

Signaling Pathways: Apoptosis; Autophagy; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling

 

Solubility: Soluble in Water; soluble in Ethanol. Insoluble in DMSO.

 

Isomeric SMILES: CCCCCCCCCCCCCCCCCCOP(=O)([O-])OC1CC[N+](CC1)(C)C  

 

InChIKey: SZFPYBIJACMNJV-UHFFFAOYSA-N  

 

InChI: InChI=1S/C25H52NO4P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29-31(27,28)30-25-20-22-26(2,3)23-21-25/h25H,4-24H2,1-3H3

 

Attribute
[Chem Name]	1,1-Dimethylpiperidin-1-ium-4-yl octadecyl phosphate
[Synonym]	Perifosine; KRX-0401; NSC-639966; D-21266; NKA17
[CAS No.]	157716-52-4
[EINECS]	690-653-3
[MDL No.]	MFCD00927554
[Formula]	C25H52NO4P
[Molecular]	461.663
[Form]	White to beige
[Storage]	Sealed in dry. Store in freezer, under -20°C

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