K-975 is a potent, selective and orally active TEAD inhibitor that directly inhibits YAP/TAZ-TEAD protein-protein interactions and has shown effective antitumor effects in malignant pleural mesothelioma.

 

Brand: BCM

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

Isomeric SMILES: CC1=C(C=C(C=C1)NC(=O)C=C)OC2=CC=C(C=C2)Cl  

 

InChIKey: KPXAHQSIROUBPH-UHFFFAOYSA-N  

 

InChI: InChI=1S/C16H14ClNO2/c1-3-16(19)18-13-7-4-11(2)15(10-13)20-14-8-5-12(17)6-9-14/h3-10H,1H2,2H3,(H,18,19) 

 

Attribute
[Chem Name]	N-[3-(4-chlorophenoxy)-4-methylphenyl]prop-2-enamide
[Synonym]	K-975; K975
[CAS No.]	2563855-03-6
[MDL No.]	MFCD34179527
[Formula]	C16H14ClNO2
[Molecular]	287.74
[Form]	White to off-white solid
[Storage]	Store at -20°C, and protect from light

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