Emtricitabine (BW1592, FTC) is a novel nucleoside agent with inhibitory activity against the human immunodeficiency viruses HIV and HBV. It is a reverse transcriptase inhibitor with a half-life of 39 h in cells.

 

Brand: BCM

 

Melting Point: 136-140°C

 

Specific Rotation: D25 -133.60° (c = 0.23 in MeOH)

 

Boiling Point: 443.3±55.0 °C(Predicted)

 

pKa: 13.83±0.10(Predicted)

 

λmax: 280nm(H2O)(lit.)

 

Solubility: Soluble in DMSO; soluble in Water; soluble in Ethanol.

 

Isomeric SMILES: C1[C@H](O[C@H](S1)CO)N2C=C(C(=NC2=O)N)F  

 

InChIKey: XQSPYNMVSIKCOC-NTSWFWBYSA-N  

 

InChI: InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m0/s1

 

Attribute
[Chem Name]	4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
[Synonym]	Emtritabine; BW 1592; FTC
[CAS No.]	143491-57-0
[EINECS]	604-363-1
[MDL No.]	MFCD00870151
[Formula]	C8H10FN3O3S
[Molecular]	247.25
[Form]	White to Pale Yellow Solid
[Storage]	Keep in dark place. Inert atmosphere, 2-8°C

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