Xanthohumol, an isopentenated chalcone from hops, inhibits COX-1 and COX-2 activity and exhibits chemoppreventative effects. Xanthohumol inhibited diacylglycerol acyltransferase 1 (DGAT1) and DGAT2 with an IC50 value of 40 μM. Xanthohumol is also a potent antiviral agent against a range of DNA and RNA viruses. Xanthohumol can induce growth arrest and apoptosis in tumor cells. Phase 1.

 

Brand: BCM

 

Melting Point: 157-159℃

 

Boiling Point: 576.5±50.0 °C(Predicted)

 

pKa: 7.59±0.45(Predicted)

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

GHS: GHS07,GHS09

 

Isomeric SMILES: CC(=CCC1=C(C(=C(C=C1O)OC)C(=O)/C=C/C2=CC=C(C=C2)O)O)C  

 

InChIKey: ORXQGKIUCDPEAJ-YRNVUSSQSA-N  

 

InChI: InChI=1S/C21H22O5/c1-13(2)4-10-16-18(24)12-19(26-3)20(21(16)25)17(23)11-7-14-5-8-15(22)9-6-14/h4-9,11-12,22,24-25H,10H2,1-3H3/b11-7+

 

Attribute
[Chem Name]	(E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
[Synonym]	Xanthohumol
[CAS No.]	6754-58-1
[EINECS]	614-078-4
[MDL No.]	MFCD00210576
[Formula]	C21H22O5
[Molecular]	354.4
[Form]	Yellow Powder
[Storage]	Keep in dark place. Inert atmosphere, 2-8°C

Goods Tag