FIPI (5-Fluoro-2-indolyl deschlorohalopemide), a derivative of halopemide, is a potent and selective inhibitor of phospholipase D. The IC50 values for PLD1 and PLD2 are 25 nM and 20 nM, respectively.

 

Brand: BCM

 

Target: IC50: 25 nM (PLD1), 20 nM (PLD2)

 

Solubility: Soluble in DMSO. Insoluble in Ethanol; insoluble in Water.

 

Isomeric SMILES: C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCNC(=O)C4=CC5=C(N4)C=CC(=C5)F  

 

InChIKey: LHABRXRGDLASIH-UHFFFAOYSA-N  

 

InChI: InChI=1S/C23H24FN5O2/c24-16-5-6-18-15(13-16)14-20(26-18)22(30)25-9-12-28-10-7-17(8-11-28)29-21-4-2-1-3-19(21)27-23(29)31/h1-6,13-14,17,26H,7-12H2,(H,25,30)(H,27,31)

 

Attribute
[Chem Name]	5-fluoro-N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1H-indole-2-carboxamide
[Synonym]	FIPI; 5-Fluoro-2-indolyl deschlorohalopemide
[CAS No.]	939055-18-2
[MDL No.]	MFCD18382115
[Formula]	C23H24FN5O2
[Molecular]	421.47
[Form]	Powder
[Storage]	Store at -20°C

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