ETP-46464 is a potent, selective ATR inhibitor with an IC50 of 25 nM.

 

Brand: BCM

 

Target: ATR:25nM

 

Boiling Point: 709.3±60.0 °C at 760 mmHg

 

pKa: 5.10±0.20(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Ethanol; insoluble in Water. 

 

Isomeric SMILES: CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3COC2=O)C5=CC6=CC=CC=C6N=C5  

 

InChIKey: DPLMXAYKJZOTKO-UHFFFAOYSA-N  

 

InChI: InChI=1S/C30H22N4O2/c1-30(2,18-31)23-8-10-24(11-9-23)34-28-22(17-36-29(34)35)16-33-27-12-7-19(14-25(27)28)21-13-20-5-3-4-6-26(20)32-15-21/h3-16H,17H2,1-2H3

 

Attribute
[Chem Name]	2-methyl-2-[4-(2-oxo-9-quinolin-3-yl-4H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl]propanenitrile
[Synonym]	ETP-46464
[CAS No.]	1345675-02-6
[MDL No.]	MFCD23160051
[Formula]	C30H22N4O2
[Molecular]	470.52
[Form]	Solid
[Storage]	Store at -20°C

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