HA15 is a specific target for HSPA5 (Heat shock 70kDa protein 5) and also known as Immunoglobulin heavy-chain-binding protein (BiP) or Grp78 The small molecule (glucose-regulated protein 78). The melanoma cells tested showed antitumor activity, including cells isolated from patients and cells resistant to BRAF inhibitors.

 

Brand: BCM

 

Target: HSP; GPR; Autophagy; Apoptosis; Others

 

Signaling Pathways: Apoptosis; Endocrinology/Hormones; Autophagy; GPCR/G Protein; Metabolism; Cytoskeletal Signaling; Others

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

GHS: GHS07

 

Isomeric SMILES: CC(=O)NC1=NC(=CS1)C2=CC(=CC=C2)NS(=O)(=O)C3=CC=CC4=C3C=CC=C4N(C)C  

 

InChIKey: LBSMEKVVMYSTIH-UHFFFAOYSA-N  

 

InChI: InChI=1S/C23H22N4O3S2/c1-15(28)24-23-25-20(14-31-23)16-7-4-8-17(13-16)26-32(29,30)22-12-6-9-18-19(22)10-5-11-21(18)27(2)3/h4-14,26H,1-3H3,(H,24,25,28)

 

Attribute
[Chem Name]	N-[4-[3-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]phenyl]-1,3-thiazol-2-yl]acetamide
[Synonym]	HA-15; HA15
[CAS No.]	1609402-14-3
[EINECS]	604-604-1
[MDL No.]	MFCD30377202
[Formula]	C23H22N4O3S2
[Molecular]	466.58
[Form]	A solid
[Storage]	Keep in dark place. Inert atmosphere. Room temperature

Goods Tag